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Research
and teaching activities
I am presently
working as a research professor at Myongji University, South Korea. I have
continued my work on biosensors since 2000 when I started my Ph.D. on
development of clinical and environmental sensors at Bhabha Atomic Research
Centre, Mumbai, India and had a close collaboration with Indian Institute of
Technology, Bombay. During my brief postdoc tenure at Indian Institute of
Technology, Bombay and during tenures of postdoc/research professor at
Myongji University, South Korea, I was engaged in designing portable
biosensors for clinical applications, while leading a research team
comprising of Ph.D. and undergraduate students. In the span of time, I
successfully completed a number of academic projects on design and
development of standalone bench-top prototypes biosensors and finding new
immobilization matrices and stabilization of biomaterials therein. Some of
those notable works include:
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Developed
Potentiostat array controlled with LabVIEW based GUI for use in
microfluidic chronoamperometric, voltammetric and pulsed amperometric
detection. The process for filing a Korean patent for this instrument is
underway. This instrument is presently operational at Department of
Nanoscience & Engineering, Myongji University, South Korea and is used
for academic research purposes.
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Developed
capillary electrophoresis amperometric detectors for
triazine herbicides, and for separation and detection of cysteine and
homocysteine from serum samples.
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Fabricated
OTFT based biosensor for detecting DNA hybridization and PCR
lab-on-a-chip device for rapid genetic analysis and filed two Korean
patents.
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Developed
integrated microfluidic lab-on-a-chip (LOC) device for PCR based
detection of cancerous cells and DNA amplification. The miniature
microfluidic chip was developed by on-chip-integration of
electrochemical cell lysis, CE-AD detector for DNA analysis and ITO
microheater based PCR amplification of template DNA.
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Developed
capillary electrophoresis amperometric detectors against DNA, dopamine,
catechol and endocrine disruptors.
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Developed
PDMS based micropump & microvalve for integration onto PCR
lab-on-a-chip.
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Developed
biosensors for methyl parathion (optical), urea (potentiometric),
glucose and catalase (amperometric), urea (conductometric) and creatine
kinase -MB (capacitive).
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Immobilization and stabilization of enzymes and microbial cells in
electrochemically and radiation polymerized synthetic polymers such as
polyaniline, polypyrrole, polyHEMA and copolymers of polyacrylamide and
polyvinyl alcohol.
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Fabricated
computer controlled dissolved oxygen meter, sensitive to parts per
trillion (ppt), for assay of catalase in pathological samples, cell and
tissue preparations and for developing multi-purpose benchtop
glucometer. The DO meter comprised of on-shelf DO probe and op-amp based
electronic assembly housed in shielded compartment and the computer
interface was developed using Labview software. The instrument is
presently operational at Enzyme and Microbial Technology section, Bhabha
Atomic Research Centre, India and is used for academic research
purposes.
-
Developed
computer controlled pH meter, sensitive to ninth decimal of pH, for
standalone potentiometric clinical urea biosensor. The pH meter
comprised of commercial pH probe and op-amp based electronic assembly
housed in shielded box and the computer interface was developed using
Labview software. This instrument is presently operational at Enzyme and
Microbial Technology section, Bhabha Atomic Research Centre, India and
is used for academic research purposes.
Academic
achievements
During my
tenure as Assistant Professor in School of Biotechnology, KIIT
University, India, I have been instrumental in formalizing MoU
(memorandum of understanding) for collaboration between Nano-Bio
Research Centre of Myongji University, South Korea and School of
Biotechnology, KIIT University, Bhubaneswar. The second step was to
ensure training of KIIT School of Biotechnology students at the Korean
Research centre.
Further, my Biosensor and Bioelectronics research group at KIIT
University and Nano Electronics and System Laboratory, Myongji
University, South Korea formalized a mutual MoA (memorandum of
agreement) to expand the scientific collaboration and exchange of
faculty and students. I was subsequently invited to South Korean lab as
visiting research professor to extend my help in projects related to our
common interests. I latter chose to continue at Myongji University on
the position of Research professor due to interest in ongoing research.
Teaching
Experience (Masters/postgraduate level)
Theory (at Myongji University)
(Course # 1737) Special issues in electrical and electronic materials
(sensors, microfabrication and smart materials); (Course #1738) Electrochemical engineering
Theory (at KIIT University)
Biochemistry; Biophysics
and Structural Biology; Food and Industrial Microbiology;
Applied & Advanced
Biotechnology
Laboratory (at KIIT University)
Industrial and Environmental Microbiology Lab, Chemical and
pharmaceuticals biotechnology lab, Industrial Biotechnology Lab,
Molecular Biology Lab, Computation Lab (online security and networking),
Animal and plant biotechnology Lab.
Research students
guided (Post graduate level)
2010 Rohit Chand, Microchip capillary electrophoresis device for
amperometric detection of DNA
Also co-guided/co-guiding several post graduate and Ph.D. students at
Myongji University, South Korea.
I worked under guidance of following eminent scientists
Prof. Yong-Sang Kim, Department of Nanoscience and Engineering, Myongji University, Yongin,
South Korea E-mail: kys [at] mju.ac.kr Phone:
Prof. Dr. S. F. D'Souza, Outstanding
Scientist, Associate Director, Bioscience Group, Bhabha Atomic Research Center, Trombay, Mumbai, 400085, E-mail: sfdsouza
[at] barc.gov.in Phone: +91-22-2559-3632
Prof. A. Q. Contractor, Head, Department of Chemistry, Indian Institute of Technology, Powai, Mumbai, 400076, E-mail: aqcontractor
[at] iitb.ac.in Phone: +91-22-2576-7151
Prof. Dr. S. K. Apte, Associate Director (B), Bioscience Group, Bhabha Atomic Research Centre, Trombay, Mumbai, Maharashtra, India. 400085.
E-mail: aptesk [at] barc.gov.in Phone: +91-22-25595342
Prof. V. R. Rao,
Department of Electrical Engineering, Indian Institute of Technology Bombay,
Mumbai, India
Prof. S.
Mukherji,
Associate
Professor, Biomedical Engineering Group, Indian Institute of Technology, Powai, Mumbai, 400076, E-mail:
mukherji [at] iitb.ac.in Phone: +91-22-2576-7767
Dr. (Mrs.) Anita Topkar, Scientist, Electronics Division, Bhabha Atomic Research Center, Trombay, Mumbai, 400085, E-mail: anita
[at] barc.gov.in Phone: +91-22-7652-2059
Dr. (Mrs.) Aruna Bhatia, Head, Department of Biotechnology, Punjabi University, Patiala, Punjab
Prof. Chanchal Mitra, Department of Chemistry, Hyderabad Central University, Hyderabad, Andhra Pradesh
Dr. Pinaki Sar, Department of Biotechnology, Indian Institute of Technology, Kharagpur, West Bengal
And of course with many other scientists and engineers, who happens to be my
colleagues and mentor and guide on several occasions.
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